The poster presentation will highlight the differentiated effects of ADX-102 on inflammatory cell migration and activation, lung function, and biochemical mediators of inflammation in a mouse model of endotoxin-induced lung injury.
ADX-102, a novel aldehyde sequestering agent, has been shown in animal models to reduce pro-inflammatory cytokines, decrease tissue edema in allergic and contact dermatitis, reduce healing time and fibrosis in radiation-induced mucositis, and diminish inflammatory pain. In Phase 2 clinical trials in patients with noninfectious anterior uveitis and allergic conjunctivitis, two ocular inflammatory diseases, ADX-102 was statistically superior to control in reducing inflammation.
Details of the presentation are as follows:
Activity of the novel aldehyde trap, ADX-102, in LPS-induced
About Aldeyra Therapeutics
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