Accounting Policies [Abstract] Accounting Policies [Abstract] Accounts Payable and Accrued Liabilities Disclosure [Text Block] Accrued Expenses Accounts Payable, Current Accounts payable Accretion Of Discounts And Issuance Costs On Preferred Stock Accretion Of Discounts And Issuance Costs On Preferred Stock Accretion of discounts and issuance costs on preferred stock Accrual for Taxes Other than Income Taxes, Current Accounting services, taxes and other Accrued Deferred Offering Costs Accrued Deferred Offering Costs Accrued deferred offering costs Accrued Interest On Convertible Notes Payable Related Parties Accrued Interest On Convertible Notes Payable Related Parties Accrued interest on convertible notes payable - related parties Accrued Liabilities and Other Liabilities Total accrued expenses Accrued Liabilities, Current Accrued expenses Accrued Payroll Taxes, Current Compensation accruals and payroll taxes Accrued Professional Fees, Current Legal expenses Accrued Research And Development Expense Current Accrued Research And Development Expense Current Research and development expenses Accumulated Deficit during Development Stage [Member] Accumulated Deficit [Member] Additional Paid in Capital Additional paid-in capital Additional Paid in Capital, Common Stock Additional pain-in capital Additional Paid-in Capital [Member] Additional Paid-in Capital [Member] Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value To President and CEO Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value To President and CEO President and CEO contributed services Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net income (loss) to net cash used in operating activities: Aggregate Development And Regulatory Milestone Payments To Licensor Aggregate Development And Regulatory Milestone Payments To Licensor Milestone payments upon reaching development and regulatory milestone Aggregate Offering Price Of Common Stock Aggregate Offering Price Of Common Stock Aggregate offering price Allocated Share-based Compensation Expense Total stock-based compensation expense Allocation of fair value of investor purchase rights to redeemable convertible preferred stock. Allocation Of Fair Value Of Investor Purchase Rights To Redeemable Convertible Preferred Stock Allocation of fair value of investor purchase rights to redeemable convertible preferred stock Allocation Of Fair Value Of Investor Right To Series B Preferred Stock Allocation Of Fair Value Of Investor Right To Seriesb Preferred Stock Allocation of fair value of investor right to Series B preferred stock Amendment Flag Amendment Flag Amortization of Debt Discount (Premium) Amortization of debt discount - non-cash interest expense Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Total of common stock equivalents Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Assets Total assets Assets [Abstract] ASSETS Assets, Current Total current assets Assets, Current [Abstract] Current assets: Assets, Fair Value Disclosure Assets measured at fair value on a recurring basis Average Trading Volume Of Common Stock Average Trading Volume Of Common Stock Trading volume of common stock Award Type [Axis] Award Type [Axis] Basis of Accounting [Text Block] Basis of Presentation Disclosure of accounting policy for basis of presentation and management plan. Basis Of Presentation And Management Plan Policy [Text Block] Basis of Presentation and Management's Plans Cash and Cash Equivalents, at Carrying Value CASH AND CASH EQUIVALENTS, END OF PERIOD CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD Cash and cash equivalents Cash and Cash Equivalents, Period Increase (Decrease) NET INCREASE IN CASH Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Cash Reserve For Indemnities And Guarantees Cash Reserve For Indemnities And Guarantees Reserve for indemnification Change In Fair Value Of Warrant Liabilities Purchase Right And Warrant Purchase Rights Change In Fair Value Of Warrant Liabilities Purchase Right And Warrant Purchase Rights Change in fair value of warrant liability, purchase rights and warrant purchase rights Class of Stock [Domain] Class of Stock [Domain] Class of Stock [Line Items] Class of Stock [Line Items] Class of Warrant or Right, Date from which Warrants or Rights Exercisable Warrants exercisable date Class Of Warrant Or Right Exercisable Class Of Warrant Or Right Exercisable Warrant exercisable Class Of Warrant Or Right Exercisable Term Class Of Warrant Or Right Exercisable Term Warrant exercisable, term Class of Warrant or Right, Exercise Price of Warrants or Rights Common stock exercise price Exercise price of warrants per share Class of Warrant or Right [Line Items] Class of Warrant or Right [Line Items] Class of Warrant or Right, Number of Securities Called by Warrants or Rights Common stock purchased Warrants to purchase shares Class of Warrant or Right [Table] Class of Warrant or Right [Table] Class Of Warrants Rights Preference Share Conversion Ratio Class Of Warrants Rights Preference Share Conversion Ratio Conversion rate of warrants to preferred stock purchased Commitments and Contingencies Commitments and contingencies (Note 13) Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Common Stock [Member] Common Voting Stock [Member] Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Common Stock, Value, Issued Common stock, non-voting, $0.001 par value; none authorized, issued and outstanding as of December 31, 2014; 65,000,000 authorized, none issued and outstanding as of December 31, 2013 Compensation Related Costs, Policy [Policy Text Block] Stock-Based Compensation Components of Deferred Tax Assets and Liabilities [Abstract] Components of Deferred Tax Assets and Liabilities [Abstract] Comprehensive Income, Policy [Policy Text Block] Comprehensive (Loss) Income Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk Consultants. Consultants [Member] Consultants [Member] Contributed service fees. Contributed Service Fees Contributed services fee to President and Chief Executive Officer Contributed service fees reduction amount. Contributed Service Fees Reduction Amount Reduction in contribution service fee A description of contributed services. Contributed Services Description Contributed services description Conversion of Stock, Amount Converted Conversion of Series A and B preferred stock upon closing initial public offering Gross proceeds from sale of shares Conversion of Stock, Amount Issued New shares issued, conversion amount Stock Conversion Description [Axis] Stock Conversion Description [Axis] Conversion of Stock, Name [Domain] Conversion of Stock, Name [Domain] Conversion of Stock, Shares Converted Conversion of preferred stock into common stock Conversion of Stock, Shares Issued New shares issued Convertible Debt Securities [Member] Convertible Note Payable-Related Parties [Member] Convertible Notes Payable, Current Convertible notes payable - related parties Convertible notes payable disclosure. Convertible Notes Payable Disclosure [Text Block] Convertible Notes Payable - Related Parties Convertible Notes Payable [Member] Convertible Note Payable-Related Parties [Member] Convertible Preferred Stock Converted to Other Securities Conversion of Preferred Convertible Preferred Stock, Shares Issued upon Conversion Conversion of preferred stock into common stock Conversion of Preferred, Shares Convertible Preferred Stock Warrant Liability [Member] Convertible Preferred Stock Warrant Liability [Member] Preferred Stock Warrant Liability [Member] Credit Facility [Axis] Credit Facility [Axis] Credit Facility [Domain] Credit Facility [Domain] Current Fiscal Year End Date Current Fiscal Year End Date Debt Conversion, Converted Instrument, Amount Conversion of notes payable Debt Conversion, Converted Instrument, Expiration or Due Date, Month and Year Due and payable date of convertible note Debt Conversion, Converted Instrument, Shares Issued Converted into common stock Debt Disclosure [Abstract] Debt Disclosure [Abstract] Debt Disclosure [Text Block] Credit Facility Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument, Basis Spread on Variable Rate Debt instrument variable annual interest rate Debt Instrument, Face Amount Convertible promissory note Convertible promissory note principal amount Debt Instrument Fair Value Carrying Value [Abstract] Debt Instrument Fair Value Carrying Value [Abstract] Debt Instrument Fair Value Carrying Value [Abstract] Debt Instrument, Interest Rate, Stated Percentage Convertible note interest rate Convertible promissory note interest rate Debt Instrument Maturity Date Amended Debt Instrument Maturity Date Amended Convertible note maturity extended date Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Debt Instrument, Unamortized Discount Net of debt discount amount Deemed dividend preferred stock. Deemed Dividend Preferred Stock Deemed dividend Deferred Offering Costs, Noncurrent Deferred Offering Costs, Noncurrent Deferred offering costs Deferred Offering Costs Not Yet Paid Deferred Offering Costs Not Yet Paid Deferred offering costs not yet paid Deferred Offering Costs Paid By Cash Deferred Offering Costs Paid By Cash Cash paid for deferred offering costs Deferred Tax Assets, Goodwill and Intangible Assets Intangibles - net Deferred Tax Assets, in Process Research and Development Increasing in research activities Deferred Tax Assets, Net Net deferred tax assets (liabilities) Deferred Tax Assets Note Discounts Deferred Tax Assets Note Discounts Note discounts Deferred Tax Assets, Operating Loss Carryforwards, State and Local Federal & State NOL carryforward Deferred Tax Assets, Other Other assets Deferred Tax Assets, Property, Plant and Equipment Fixed assets Deferred Tax Assets, Tax Credit Carryforwards, Research Federal & State R&D credit carryforward Deferred Tax Assets Tax Credit Carryforwards Research Expiration Year Deferred Tax Assets Tax Credit Carryforwards Research Expiration Year Increasing in research activities expire period Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost Stock options Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities Accounts payable and accrued expenses Deferred Tax Assets, Valuation Allowance Less valuation allowance Deferred tax assets valuation allowance percentage. Deferred Tax Assets Valuation Allowance Percentage Deferred tax assets valuation allowance Depreciation Depreciation Derivative, Gain (Loss) on Derivative, Net Less: change in fair value of derivative liabilities Derivative Liability, Noncurrent Convertible preferred stock warrant liability Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock Incentive Plan Dividends, Preferred Stock, Cash Deemed dividend Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Period End Date Document Period End Date Document Type Document Type Domain Partners VI LP [Member] Domain Partners VI LP [Member] Domain Partners VI LP [Member] Domestic Tax Authority [Member] Federal [Member] Earnings Per Share [Abstract] Earnings Per Share [Abstract] Earnings Per Share, Basic Basic Earnings Per Share, Basic and Diluted [Abstract] Net (loss) income per share attributable to common stockholders: Net income (loss) per share: Earnings Per Share, Basic and Diluted, Other Disclosures [Abstract] Weighted average common shares outstanding: Earnings Per Share, Diluted Diluted Weighted average number of common share, diluted per share Earnings Per Share, Policy [Policy Text Block] Net (Loss) Income Applicable to Common Stock Earnings Per Share [Text Block] Net (Loss) Income Attributable to Common Stockholders Effective Income Tax Rate Reconciliation, Percent Effective tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Statutory tax rate Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Change in valuation allowance Effective Income Tax 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Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Entity Current Reporting Status Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Public Float Entity Public Float Entity Registrant Name Entity Registrant Name Entity Voluntary Filers Entity Voluntary Filers Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Equity [Abstract] Equity [Abstract] Equity Component [Domain] Equity Component [Domain] Equity Method Investments And Cost Method Investments [Abstract] Equity Method Investments And Cost Method Investments [Abstract] Equity Method Investments And Cost Method Investments [Abstract] Estimated Fair Value of Preferred Shares Estimated Fair Value of Preferred Shares Fair value of shares Excess Of Fair Value Over Share Issue Price Excess Of Fair Value Over Share Issue Price Amount of value received in excess of issuance price Exercise Of Warrant Purchase Rights Into Warrants Exercise Of Warrant Purchase Rights Into Warrants Exercise of Series B warrant purchase rights into warrants Exercise of warrants purchase rights into Series B Warrants Expiration Of Warrant Expiration Of Warrant Warrant expiration date Fair Value Adjustment Gain Losses Fair Value Adjustment Gain Losses Gain on fair value measurement adjustment Fair Value Adjustment Of Convertible Preferred Stock Rights And Rights Option Liabilities Fair Value Adjustment Of Convertible Preferred Stock Rights And Rights Option Liabilities Change in fair value of convertible preferred stock rights and rights option liabilities Fair Value Adjustment of Warrants Change in fair value Change in fair value of preferred stock warrant liabilities Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table Text Block] Schedule of Inputs Used by Instrument to Determine the Fair Value Measurements Fair Value Assumptions, Exercise Price Preferred stock warrant liability, Exercise price Fair Value Assumptions, Expected Dividend Rate Preferred stock warrant liability, Expected dividend yield Fair Value Assumptions, Expected Term Expected term Preferred stock warrant liability, Expected life (years) Fair Value Assumptions, Expected Volatility Rate Preferred stock warrant liability, Anticipated volatility Volatility rate Fair Value Assumptions, Risk Free Interest Rate Preferred stock warrant liability, Risk free interest rate Risk-free interest rate Fair Value, Hierarchy [Axis] Fair Value, Hierarchy [Axis] Liability Class [Axis] Liability Class [Axis] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Fair Value Measurements Fair Value, Inputs, Level 1 [Member] Level 1 [Member] Fair Value, Inputs, Level 2 [Member] Level 2 [Member] Fair Value, Inputs, Level 3 [Member] Level 3 [Member] Fair Value, Liabilities Measured on Recurring Basis [Table Text Block] Schedule of Liabilities Measured at Fair Value on Recurring Basis Fair Value by Liability Class [Domain] Fair Value by Liability Class [Domain] Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair value [Member] Fair value [Member] Fair Value [Member] Fair Value Of Assets And Liabilities Measured On Non Recurring Basis [Line Items] Fair Value Of Assets And Liabilities Measured On Non Recurring Basis [Line Items] Fair Value Of Assets And Liabilities Measured On Non Recurring Basis [Line Items] Fair Value Of Conversion Of Convertible Preferred Stock Warrant Fair Value Of Conversion Of Convertible Preferred Stock Warrant Net exercise of Series A and B Warrants Fair Value of Financial Instruments, Policy [Policy Text Block] Fair Value of Financial Instruments Fair Value Of Warrants Fair Value Of Warrants Warrants, fair value Fair Value Of Warrants Issued In Connection With Credit Facility Fair Value Of Warrants Issued In Connection With Credit Facility Fair value warrants in connection with credit facility Warrant liability - Series B Financial Instrument [Axis] Financial Instrument [Axis] Class of Financing Receivable [Axis] Class of Financing Receivable [Axis] Class of Financing Receivable [Domain] Class of Financing Receivable [Domain] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] General and Administrative Expense General and administrative General and Administrative Expense [Member] General and Administrative Expenses [Member] Grant two. Grant Two [Member] Two Grants [Member] Income Statement [Abstract] Income Statement [Abstract] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Income Tax Authority [Axis] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Income Tax Contingency [Line Items] Income Tax Contingency [Line Items] Income Tax Contingency [Table] Income Tax Contingency [Table] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Income Tax Expense (Benefit) Provision for income tax benefit Income Tax, Policy [Policy Text Block] Income Taxes Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses Increase (Decrease) in Notes Payable, Related Parties Accrued interest on convertible notes related parties Increase (Decrease) in Operating Capital [Abstract] Change in assets and liabilities: (Increase) decrease Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase in common stock. Increase In Common Stock Increase in common stock outstanding Increase percentage of common stock outstanding. Increase Percentage Of Common Stock Outstanding Percentage of increase in common shares outstanding Incremental Common Shares Attributable to Dilutive Effect of Call Options and Warrants Warrants (treasury stock) Incremental Common Shares Attributable to Dilutive Effect of Equity Unit Purchase Agreements Warrants purchase rights (treasury stock) Indemnification Obligations Claims Outstanding Indemnification Obligations Claims Outstanding Outstanding material claims Initial Offering Period Initial public offering Initial Public Offering Date Of Completion Initial Public Offering Date Of Completion Initial public offering completion date Intangible Assets, Finite-Lived, Policy [Policy Text Block] Intellectual Property Intellectual Property [Member] Intellectual Property [Member] Interest Expense Interest expense Interest Paid Interest Interest Payable, Current Interest Interest payment period for line of credit facility Interest Payment Period For Line Of Credit Facility Credit Facility, period of interest only payments Interest Receivable Accrued interest Investment Income, Interest Interest income Investment Maturity Period Investment Maturity Period Investment maturity period Investment Warrants, Exercise Price Exercise price of warrant IPO [Member] Initial Public Offering [Member] Issuance Of Common Stock Upon Cashless Net Exercise Of Warrant Issuance Of Common Stock Upon Cashless Net Exercise Of Warrant Net exercise of warrants into common stock Issuance Of Series B Preferred Stock Net Of Issuance Costs And Warrant Liability Issuance Of Seriesb Preferred Stock Net Of Issuance Costs And Warrant Liability Issuance of Series B preferred stock, net of issuance costs and warrant liability Issuance Of Series B Preferred Stock Net Of Issuance Costs And Warrant Liability Shares Issuance Of Seriesb Preferred Stock Net Of Issuance Costs And Warrant Liability Shares Issuance of Series B preferred stock, net of issuance costs and warrant liability,shares Lease agreement area of office space. Lease Agreement Area Of Office Space Lease agreement area of office space Lessee Leasing Arrangements, Operating Leases, Term of Contract Lease agreement period Liabilities Total liabilities Liabilities [Abstract] Liabilities: Liabilities and Equity Total liabilities, redeemable convertible preferred stock and stockholders' equity (deficit) Liabilities and Equity [Abstract] LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) Liabilities, Current Total current liabilities Liabilities, Current [Abstract] Current liabilities: Financial and Nonfinancial Liabilities, Fair Value Disclosure Balance at end of period Balance at beginning of period Liabilities measured at fair value on a recurring basis License Agreement, Termination Description License Agreement, Termination Description License and supply agreement termination description Long-term Line of Credit Amount borrowing under credit facility Credit facility amount Line of Credit Facility [Abstract] Line of Credit Facility [Abstract] Line of Credit Facility, Annual Principal Payment Principal payments Lender Name [Axis] Lender Name [Axis] Line of Credit Facility, Current Borrowing Capacity Current borrowings capacity under credit facility Line of Credit Facility, Interest Rate During Period Debt instrument annual interest rate Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender [Domain] Line of Credit Facility [Line Items] Line of Credit Facility [Line Items] Line Of Credit Facility Maturity Month And Year Line Of Credit Facility Maturity Month And Year Maturity period of term loans Line of Credit Facility [Table] Line of Credit Facility [Table] Line of Credit [Member] Credit Facility [Member] Liquidity Disclosure [Policy Text Block] Liquidity Loan Repayment Term Loan Repayment Term Loan repayment period Long-term Debt Total Long-term Debt, Current Maturities Current portion of credit facility Long-term Debt, Maturities, Repayments of Principal in Next Twelve Months 2015 Long-term Debt, Maturities, Repayments of Principal in Year Four 2018 Long-term Debt, Maturities, Repayments of Principal in Year Three 2017 Long-term Debt, Maturities, Repayments of Principal in Year Two 2016 Long-term Debt, Excluding Current Maturities Credit facility, net of current portion and debt discount Maximum [Member] Maximum [Member] Minimum [Member] Minimum [Member] Monte Carlo Simulations [Member] Monte Carlo Simulations [Member] Monte Carlo Simulations [Member] Nature of Operations [Text Block] Nature of Business Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] CASH FLOWS FROM FINANCING ACTIVITIES: Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] CASH FLOWS FROM INVESTING ACTIVITIES: Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Net Exercise Of Common Stock Warrants Net Exercise Of Common Stock Warrants Net exercise of warrants Net Exercise Of Common Stock Warrants Shares Net Exercise Of Common Stock Warrants Shares Net exercise of warrants, Shares Net Income (Loss) Attributable to Parent Net income (loss) Net (loss) income and comprehensive (loss) income Net (loss) income and comprehensive (loss) income Net income Net Income (Loss) Attributable to Parent [Abstract] Numerator: Net Income (Loss) Available to Common Stockholders, Basic Net (loss) income attributable to common stockholders - basic Net (loss) income attributable to common stockholders Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Basic Net Income (Loss) Available to Common Stockholders, Diluted Net (loss) income available to common stockholders - diluted Net Income (Loss) Available to Common Stockholders, Diluted [Abstract] Diluted Net Income Loss Per Common Share [Line Items] Net Income Loss Per Common Share [Line Items] Net Income Loss Per Common Share [Line Items] Net Operating Loss Carry Forwards Expiration Year Net Operating Loss Carry Forwards Expiration Year Net operating loss carryforwards expire period New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Noncash Investing and Financing Items [Abstract] SUPPLEMENTAL DISCLOSURES OF NONCASH INVESTING AND FINANCING ACTIVITIES: Non employee stock option. Non Employee Stock Option [Member] Non-Employee Stock Options [Member] Nonoperating Income (Expense) Total other income, net Nonvoting Common Stock [Member] Common stock, non-voting [Member] Number Of Financial Institutions Number Of Financial Institutions Number of financial institution Number of incentive plans. Number Of Incentive Plans Number of incentive plans Number of Reportable Segments Number of segment Offering costs related to issuance of preferred stock. Offering Costs Related To Issuance of Preferred Stock Offeratory costs in connection with Series B redeemable convertible preferred stock issuance in accrued expenses Operating Expenses Intellectual property related expenses Operating Expenses [Abstract] Operating expenses: Operating Income (Loss) Loss from operations Operating Leases, Future Minimum Payments Due Operating lease obligations, Total Total base rent payable Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract] Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract] Operating Leases, Future Minimum Payments Due, Next Twelve Months Operating lease obligations, 2015 Operating Leases, Future Minimum Payments, Due in Three Years Operating lease obligations, 2017 Operating Leases, Future Minimum Payments, Due in Two Years Operating lease obligations, 2016 Operating Leases, Rent Expense, Net Initial base annual rent Operating Loss Carryforwards Net operating loss carryforwards Other Nonoperating Income (Expense) [Abstract] Other income (expense): Payables and Accruals [Abstract] Payables and Accruals [Abstract] Payment Of Underwriting Discounts And Commissions Payment Of Underwriting Discounts And Commissions Underwriting discounts and commissions Payments for Operating Activities [Abstract] Cash paid during the period for: Payments for (Proceeds from) Loans Receivable Advance payment received in November 2013 through term loan Payments of Stock Issuance Costs Offering costs Payments to Acquire Property, Plant, and Equipment Acquisitions of property and equipment Percentage of voting rights interest. Percentage Of Voting Rights Interest Voting rights interest Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] Plan termination date. Plan Termination Date Stock incentive plan, termination date Preferred Stock, Accretion of Redemption Discount Accretion of discounts and issuance costs on preferred stock Preferred Stock Dividends, Income Statement Impact Deemed dividend Preferred Stock [Member] Preferred Stock [Member] Preferred Stock, Par or Stated Value Per Share Preferred Stock, par value Preferred Stock Right Expiration Date Preferred Stock Right Expiration Date Rights-warrants expiration date Preferred Stock Rights Warrants Unexercised Preferred Stock Rights Warrants Unexercised Preferred stock, unexercised Preferred Stock, Shares Authorized Preferred Stock, shares authorized Preferred Stock, Shares Issued Preferred Stock, shares issued Shares issued Preferred Stock, Shares Outstanding Preferred Stock, shares outstanding Preferred Stock [Text Block] Redeemable Convertible Preferred Stock Preferred Stock, Value, Issued Preferred Stock, Fair Value Preferred stock, value Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Prepaid offering and printing costs Prepaid Offering And Printing Costs Prepaid offering and printing costs President And CEO Contributed Services President And Ceo Contributed Services President and CEO contributed services Prime Rate [Member] Prime Rate [Member] Proceeds from Issuance Initial Public Offering Proceeds from initial public offering net of underwriting discounts, commissions and offering costs Proceeds from Issuance of Common Stock Proceeds from issuance of common stock, net of issuance costs Proceeds from Issuance of Preferred Stock and Preference Stock Gross proceeds from sale of shares Proceeds from Issuance of Private Placement Private placement of common stock and warrants raised Proceeds from Issuance of Redeemable Convertible Preferred Stock Net proceeds from issuance of Series B redeemable convertible preferred stock Proceeds From Issuance Of Restricted Common Stock Proceeds From Issuance Of Restricted Common Stock Proceeds from issuance of restricted common stock Proceeds from Lines of Credit Borrowings under credit facility, net Proceeds from credit facility Proceeds from Notes Payable Proceeds from convertible notes payable - related parties Property, Plant and Equipment, Net Fixed assets, net Range [Axis] Range [Axis] Range [Domain] Range [Domain] Redeemable Convertible Preferred Stock [Member] Redeemable Convertible Preferred Stock [Member] Redemption Price Of Warrants Redemption Price Of Warrants Warrant redemption price Related Party Transaction [Axis] Related Party Transaction [Axis] Related Party Transaction Derivative Liability, Noncurrent Related Party Transaction Derivative Liability, Noncurrent Convertible preferred stock warrant liabilities - related parties Related Party Transaction [Domain] Related Party Transaction [Domain] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Related Party Transactions [Abstract] Related Party Transactions [Abstract] Related Party Transactions Disclosure [Text Block] Related Party Transactions Repayments of Lines of Credit Repayments of credit facility Research and Development Expense Research and development Research and Development Expense [Member] Research and Development Expenses [Member] Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Restricted Stock [Member] Restricted Stock [Member] Retained Earnings (Accumulated Deficit) Accumulated deficit Rights [Member] Series A Rights [Member] Sale of Stock [Domain] Sale of Stock [Domain] Sale of Stock, Number of Shares Issued in Transaction Common stock shares sold Sale of Stock, Price Per Share Common stock issued price per share Scenario, Previously Reported [Member] Scenario, Previously Reported [Member] Scenario, Unspecified [Domain] Scenario, Unspecified [Domain] Schedule of Accrued Liabilities [Table Text Block] Schedule of Accrued Expenses Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Computation of Diluted Weighted-Average Shares Outstanding Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Components of Deferred Tax Assets and Liabilities Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Computation of Basic and Diluted Net (Loss) Income per Share Attributable to Common Stockholders Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Summary of Statutory Tax Rates and Effective Tax Rates Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of Stock-Based Compensation Expense Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Schedule of Future Minimum Payments Under Non-Cancelable Operating Leases Schedule of Maturities of Long-term Debt [Table Text Block] Schedule of Future Maturities of Existing Term Loans Schedule Of Net Income Loss Per Common Share [Table] Schedule Of Net Income Loss Per Common Share [Table] Schedule Of Net Income Loss Per Common Share [Table] Schedule Of Reconciliation Of Asset Or Liability Measured At Fair Value On Recurring Basis Significant Unobservable Inputs Level Three Table [Text Block] Schedule Of Reconciliation Of Asset Or Liability Measured At Fair Value On Recurring Basis Significant Unobservable Inputs Level Three Table [Text Block] Schedule of Reconciliation of Liabilities Measured at Fair Value on Recurring Basis Schedule of Related Party Transactions, by Related Party [Table] Schedule of Related Party Transactions, by Related Party [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of Stock Option Activity Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Fair Value of Stock Option Assumptions Schedule of Short-term Debt [Table] Schedule of Short-term Debt [Table] Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Schedule of stock option exercise activity table. Schedule Of Stock Option Exercise Activity Table [Text Block] Summary of Stock Options Outstanding Second Tranche [Member] Second Tranche [Member] Second Tranche [Member] Segment Reporting, Policy [Policy Text Block] Segment Information Series A and series B preferred stock. Series A And Series B Preferred Stock [Member] Series A and Series B Preferred Stock [Member] Series A Preferred Stock [Member] Series A Preferred Stock [Member] Series B Preferred Stock [Member] Series B Preferred Stock [Member] Series B Warrant [Member] Series B Warrant [Member] Series B Warrants [Member] Series B Rights Warrants [Member] Series B Rights Warrants [Member] Series B Rights-Warrants [Member] Share-based Compensation Stock-based compensation Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Stock option vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage Percentage of rights transferred to shareholders Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Stock option granted in term years Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Exercise Price Exercise price Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected life (years) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Anticipated volatility Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk free interest rate Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Issuance of common stock authorized Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Common stock available for issuance Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Number Exercisable Options exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Exercisable Shares Weighted-Average Remaining Contractual Life Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Number of options granted Stock Options, Granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant date fair value Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Aggregate intrinsic value of stock options Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Stock Options Outstanding, Ending Balance Stock Options Outstanding, Beginning Balance Options to purchase of shares of common stock Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Period Increase (Decrease) Common stock issued under 2013 plan Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Ending Balance Weighted Average Exercise Price, Beginning Balance Exercise price per share of common stock Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Outstanding Shares Weighted-Average Remaining Contractual Life Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Intrinsic value of options vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Weighted average exercise price of shares vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Fair value of award Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent Fair value of a common stock percentage Share-based Compensation Arrangement by Share-based Payment Award, Terms of Award Stock incentive plans, contractual term Equity Award [Domain] Equity Award [Domain] Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Exercise price per share of common stock Weighted Average Exercise Price, Granted Share Price Preferred stock warrant liability, Estimated stock price Share price of common stock Estimated stock price Fair value of share, per share Shares, Issued Common stock issued in initial public offering Shares Issued, Price Per Share Shares issued, per share price Shares, Outstanding Ending Balance, Shares Beginning Balance, Shares Short-term Debt [Line Items] Short-term Debt [Line Items] Short-term Debt, Type [Axis] Short-term Debt, Type [Axis] Short-term Debt, Type [Domain] Short-term Debt, Type [Domain] Square One Bank [Member] Square One Bank [Member] Square One Bank [Member] State and Local Jurisdiction [Member] State [Member] Class of Stock [Axis] Class of Stock [Axis] Equity Components [Axis] Equity Components [Axis] Statement [Line Items] Statement [Line Items] Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Scenario [Axis] Scenario [Axis] Statement [Table] Statement [Table] Stockholders' Equity Attributable to Parent Ending Balance Beginning Balance Total stockholders' equity (deficit) Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity (deficit): Stock Issued During Period, Shares, Conversion of Convertible Securities Conversion feature on convertible promissory note, Shares Stock Issued During Period, Shares, New Issues Issuance of common stock, net of issuance costs, Shares Stock Issued During Period, Shares, Restricted Stock Award, Gross Issuance of restricted stock awards, Shares Restricted stock awards issued Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Shares purchased by investors Stock option exercised Stock Issued During Period, Value, Conversion of Convertible Securities Beneficial conversion feature on convertible promissory note Stock Issued During Period, Value, New Issues Issuance of common stock, net of issuance costs Stock Issued During Period, Value, Restricted Stock Award, Gross Issuance of restricted stock awards Equity Option [Member] Options to Purchase Common Stock [Member] Stock or Unit Option Plan Expense Expense relating to options Stock purchase warrants. Stock Purchase Warrants [Text Block] Stock Purchase Warrants Subsequent Event [Member] Subsequent Event [Member] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Sale of Stock [Axis] Sale of Stock [Axis] Supplemental Cash Flow Information [Abstract] SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION: Temporary Equity [Abstract] Redeemable convertible preferred stock: Temporary Equity, Accretion to Redemption Value, Adjustment Accretion of redeemable convertible preferred stock Accretion of preferred stock Temporary Equity, by Class of Stock [Table] Temporary Equity, by Class of Stock [Table] Temporary Equity, Carrying Amount, Attributable to Parent Redeemable convertible preferred stock Temporary Equity [Line Items] Temporary Equity [Line Items] Temporary Equity, Par or Stated Value Per Share Preferred Stock, par value Temporary Equity, Shares Authorized Preferred Stock, shares authorized Temporary Equity, Shares Issued Preferred Stock, shares issued Temporary Equity, Shares Outstanding Preferred Stock, shares outstanding Term Loan [Member] Term Loan [Member] Term Loan [Member] Text Block [Abstract] Text Block [Abstract] Trading Symbol Trading Symbol Tranche B Loans [Member] Tranche B Loans [Member] Tranche B Loans [Member] Financial Instruments [Domain] Financial Instruments [Domain] Two thousand and thirteen incentive plan. Two Thousand And Thirteen Incentive Plan [Member] 2013 Plan [Member] Two thousand four incentive plan. Two Thousand Four Incentive Plan [Member] 2004 Plan [Member] Two thousand ten incentive plan. Two Thousand Ten Incentive Plan [Member] 2010 Plan [Member] Undistributed Earnings (Loss) Allocated to Participating Securities, Basic Allocation of undistributed earnings to preferred stockholders Use of Estimates, Policy [Policy Text Block] Use of Estimates Variable Rate [Axis] Variable Rate [Axis] Variable Rate [Domain] Variable Rate [Domain] Voting Common Stock [Member] Voting Common Stock [Member] Common stock, voting [Member] Warrant [Member] Warrant [Member] Warrants and Rights Outstanding Warrant value Warrants expire date. Warrants Expire Date Warrants expiration date Warrants Issued To Underwriter In Initial Public Offering Warrants Issued To Underwriter In Initial Public Offering Warrants issued to underwriter in initial public offering Warrants To Purchase Convertible Preferred Stock [Member] Warrants To Purchase Convertible Preferred Stock [Member] Warrants to Purchase Preferred Stock [Member] Weighted Average Number of Shares Outstanding, Diluted Diluted Total weighted average number of common shares - diluted Weighted average number of diluted shares Weighted Average Number of Shares Outstanding, Diluted [Abstract] Diluted Weighted Average Number of Shares Outstanding, Basic Basic Weighted-average number of common shares - basic Weighted Average Number of Shares Outstanding, Basic [Abstract] Basic Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Denominator: Weighted Average Number of Shares, Treasury Stock Rights (treasury stock)