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Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by investing activities Title of 12(b) Security Title of 12(b) Security Upfront Cash Payment Upfront Cash Payment Upfront Cash Payment Credit facility, interest rate Line of Credit Facility, Interest Rate at Period End Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Forfeited Weighted-Average Grant Date Fair Value, Forfeited Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Money Market Funds [Member] Money Market Funds [Member] Related Party Related and Nonrelated Parties [Domain] Income Taxes Income Tax Disclosure [Text Block] Contingent consideration payable in stock Accrued Contingent Consideration Payable In Stock Current Accrued contingent consideration payable in stock current. Collaborative Arrangement and Arrangement Other than Collaborative [Table] Legal Entity Legal Entity [Axis] Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Change in operating assets and liabilities: Weighted Average Exercise Price, Beginning Balance Weighted Average Exercise Price, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price 2016 Employee Stock Purchase Plan [Member] Two Thousand Sixteen Employee Stock Purchase Plan [Member] 2016 employee stock purchase plan member. Income Tax Disclosure [Abstract] Fair Value, Recurring and Nonrecurring [Table] Helio Vision Acquisition Business Combination [Text Block] Additional Paid-in Capital [Member] Additional Paid-in Capital [Member] Statement of Income Location, Balance [Axis] Trading Symbol Trading Symbol Accrued compensation Employee-related Liabilities, Current Employee-related Liabilities, Current, Total Indemnification Obligations Claims Outstanding Indemnification Obligations Claims Outstanding Outstanding material claims CASH FLOWS FROM FINANCING ACTIVITIES: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Accrued Expenses Accounts Payable and Accrued Liabilities Disclosure [Text Block] Lessee, Operating Lease, Liability, to be Paid Remaining total lease payments, total 2026 remaining total lease payments Less: effect of discounting Lessee, Operating Lease, Liability, Undiscounted Excess Amount Other than Temporary Impairment, Credit Losses Recognized in Earnings, Categories of Investments [Domain] Equity Components Equity Components [Axis] Jefferies Sales Agreement [Member] Jefferies Sales Agreement [Member] Jefferies sales agreement. Nonoperating Income (Expense) Total other income, net Equity Component Equity Component [Domain] Business Acquisition Business Combination [Axis] Prepaid insurance expenses Prepaid Insurance Issuance of common stock, employee stock purchase plan, Shares Stock Issued During Period, Shares, Employee Stock Purchase Plans Research And Development Expenses [Member] Research And Development Expenses Member Research and Development Expenses [Member] Common Stock after FDA Approval prior to 10th Anniversary [Member] Common Stock After F D A Approval Prior To Tenth Anniversary [Member] Common stock after FDA approval prior to tenth anniversary. Statement of Comprehensive Income [Abstract] Unamortized Right-Of-Use asset Unamortized Right-Of-Use asset Term loan advance one member. Term Loan Advance One [Member] Term Loan Advance One [Member] Maximum [Member] Maximum [Member] Liabilities, Fair Value Disclosure, Total Liabilities measured at fair value on a recurring basis Liabilities, Fair Value Disclosure Statistical Measurement Statistical Measurement [Axis] Weighted Average Exercise Price, Exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Common stock issued in connection with Helio Vision, Inc. acquisition milestone Common Stock, Value, Issued Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Common stock, voting, $0.001 par value; 150,000,000 authorized and 60,321,068 and 60,162,773 shares issued and outstanding, respectively Cash and Cash Equivalents [Abstract] Treatment [Axis] Treatment [Axis] Term Loan Advance Three [Member] Term Loan Advance Three [Member] Term loan advance three member. Preferred Stock, Shares Authorized Preferred stock, shares authorized Debt Security Category [Axis] Schedule of Cash, and Cash Equivalents Cash, Cash Equivalent, and Investment [Table Text Block] Schedule Of Business Acquisitions By Acquisition [Table] Business Combination [Table] Entity Registrant Name Entity Registrant Name Credit Facility Debt Disclosure [Text Block] MEEI Agreement [Member] M E E I Agreement [Member] MEEI Agreement [Member] Income tax benefit Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Available for sale unrecognized loss Debt Securities, Available-for-Sale, Unrealized Loss Available for sale unrecognized loss Proceeds from Issuance of Common Stock Proceeds from issuance of common stock, net of issuance costs Proceeds from issuance of common stock, net of commissions and other offering costs Legal Proceedings [Abstract] Legal Proceedings. Contingent Consideration by Type Business Combination, Contingent Consideration, Type [Axis] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive loss Nonvested Founder Shares [Member] Nonvested Founder Shares [Member] Nonvested Founder Shares [Member]. Total assets Assets Weighted Average Contractual Term, Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Income Statement [Abstract] Schedule Of Restructuring And Related Costs [Table] Restructuring Cost [Table] Aggregate intrinsic value of options outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding Cash, Cash Equivalents and Marketable Securities Cash, Cash Equivalent, and Marketable Security [Text Block] Issuance of common stock, employee stock purchase plan, Shares Issuance of common stock, net of issuance costs, Shares Stock Issued During Period, Shares, New Issues Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Vested Business Combination [Abstract] Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Net loss per share - diluted Service Based Awards [Member] Service Based Awards [Member] Service based awards. Cash Cash Equivalents And Marketable Securities [Table] Cash Cash Equivalents And Marketable Securities [Table] Cash Cash Equivalents And Marketable Securities [Table] City Area Code City Area Code Other Comprehensive Income (Loss), Net of Tax Other Comprehensive Income (Loss), Net of Tax, Total Other comprehensive loss Reclassification of losses to net loss Credit facility amount Line of Credit Facility, Maximum Borrowing Capacity Business Acquisition [Line Items] Business Combination [Line Items] Underwritten Public Offering [Member] Underwritten Public Offering [Member] Underwritten public offering. Issuance of common stock, employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Operating leases, weighted average remaining lease term (years) Operating Lease, Weighted Average Remaining Lease Term RSU granted Stock Issued During Period, Shares, Restricted Stock Award, Gross Issuance of common stock, vested restricted stock units, Shares Tax Gross-up Payment in Event of Change of Control or Divesture [Member] Tax Gross Up Payment Change Of Control Or Divesture [Member] Tax gross-up payment, change of control or divesture. Long-Term Debt, Percentage Bearing Variable Interest, Percentage Rate Long term debt percentage Milestone [Member] Milestone [Member] Milestone. Loss from operations Operating Income (Loss) Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items] Prepaid Expenses and Other Current Assets Prepaid Expenses And Other Current Assets [Text Block] Prepaid Expenses And Other Current Assets [Text Block]. Accumulated Deficit [Member] Retained Earnings [Member] Contingent Consideration Type Business Combination, Contingent Consideration, Type [Domain] Share based compensation expense Employee Benefits and Share-Based Compensation Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Share-based Payment Arrangement, Noncash Expense, Total Commitment charge Line Of Credit Facility Commitment Charge Line of credit facility, commitment charge. Operating leases, weighted average discount rate Operating Lease, Weighted Average Discount Rate, Percent Non-current operating lease liabilities Operating Lease, Liability, Noncurrent Operating lease liabilities, long-term Fair Value, Inputs, Level 1 [Member] Class Of Stock [Line Items] Class of Stock [Line Items] Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Unamortized debt issuance costs Unamortized Debt Issuance Expense Other income (expense): Nonoperating Income (Expense) [Abstract] Computation of Diluted Weighted-Average Shares Outstanding Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Income Tax Authority Income Tax Jurisdiction [Domain] Credit facility prepayment fee percentage Line Of Credit Facility Prepayment Fee Percentage The percentage of fee if the term loan is prepaid. Entity Interactive Data Current Entity Interactive Data Current Income Statement Location Statement of Income Location, Balance [Domain] CASH FLOWS FROM OPERATING ACTIVITIES: Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Net amortization of premium on marketable securities Accretion (Amortization) of Discounts and Premiums, Investments Reverse repurchase agreements Cash equivalent - reverse repurchase agreements Cash Equivalent Reverse Repurchase Agreement Cash equivalent reverse repurchase agreement. Business combination, stock issued Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares Common Stock after FDA Approval Prior to 12th Anniversary [Member] Common Stock After F D A Approval Prior To Twelfth Anniversary [Member] Common stock after FDA approval prior to twelfth anniversary. Entity Tax Identification Number Entity Tax Identification Number Closing market value of common stock Share Price Long-term Debt, Type Long-Term Debt, Type [Axis] Local Phone Number Local Phone Number Debt Securities, Available-for-Sale, Unrealized Gain Available for sale unrecognized gain Unamortized stock-based compensation Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Unrecognized Tax Benefits, Interest on Income Taxes Expense Unrecognized Tax Benefits, Interest on Income Taxes Expense Accounting Policies [Abstract] Lessee, Operating Lease, Liability, to be Paid, Year Four Operating lease obligations, 2029 Common stock available for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Weighted average recognition period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Estimated Fair Value Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-term Investments, Total Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Entity Emerging Growth Company Entity Emerging Growth Company